MCQ Bank
BLASTX compares:
- A) Protein sequences against protein databases
- B) Protein sequences against DNA databases
- C) Nucleotide sequences against nucleotide databases
- D) Translated nucleotide sequences against protein databases
CSM stands for Hint: Protein Data Bank (PDB)
- A) Computer System Models
- B) Computer Structure Management
- C) Computer Structure Models
- D) Computer System Management
In Target–template alignment, If the user knows the structure of the template to use for modelling, the coordinates can be uploaded in PDB format (*) together with the target protein sequence.
- A) False
- B) True
- C)
- D)
A protein having instability index ................... 40 is considered as stable.
- A) Smaller than
- B) None of these
- C) Greater than
- D) Equal to
…………………. is incorrect statement regarding the terminologies of phylogenetics.
- A) Tips of the branches shows species or genes
- B) Point joining two adjacent branches represent a node
- C) Node is ancestor of extant taxa
- D) Branches shows the lines
While generating an alignment In MEGA 11, you can ------- default parameters of the selected tool. (Choose the most suitable one)
- A) Delete
- B) Edit
- C) Highlight
- D) Skip
__________ a new fold recognition method aimed particularly at detecting superfamily relationships in case of psipred
- A) GenTHREADER
- B) Uniprot
- C) BLAST
- D) MEMSAT 2
GMQE (Global Model Quality Estimation) is expressed as a number between ________
- A) 0.5 to 1
- B) Greater than 1
- C) 0 and 1
- D) Less than 0
The limitation of InterPro concerning amino acid length is:
- A) Maximum length of 400,000 amino acids
- B) There is no limitation based on amino acid length
- C) Maximum length of 40,000 amino acids
- D) Maximum length of 4000 amino acids
BLASTX searches a protein sequence database using protein sequences as queries?
- A) FALSE
- B) TRUE
- C)
- D)
According to the I-TASSER server, if the confidence score in the predicted secondary structure is near 1, it indicates:
- A) Low prediction accuracy
- B) High prediction accuracy
- C) Moderate prediction accuracy
- D) Unreliable prediction accuracy
How does the sequence alignment help in drug discovery?
- A) All of these
- B) By identifying evolutionary relationship between organisms
- C) By identifying area that might be affected by mutations or drug binding
- D) By identifying functional domains in proteins
______ is a short sequence that contains one or more conserved residues, which allow the protein to bind to a ligand and carry out a catalytic activity. Hint: InterPro
- A) Conserved site
- B) Active site
- C) PTM site
- D) Binding site