.......invokes a flexible element within the polymerase that allows a module at the front of the enzyme, containing the active site.

• A) transient excursion
• B) Scrunching and Inchworming
• C) Inchworming
• D) Scrunching

____________ is known as the minor form of the spliceosome.

• A) Special spliceosome
• B) GC-AT spliceosome
• C) AC-TG spliceosome
• D) AT-AC spliceosome

Bacteria have _________ types of RNA polymerase

• A) 3
• B) 1
• C) 2
• D) 5

In RNA splicing mature mRNA contains __________.

• A) Introns
• B) Introns and Exons
• C) 3 codons
• D) Exons

An intron is removed through two successive ____________ reactions in which phosphodiester linkages within the pre-mRNA are broken and new ones are formed

• A) Amination
• B) Deamination
• C) Transesterification
• D) Phosphorylation

____________polymerase can initiate a new RNA chain on a DNA template

• A) DNA
• B) RNA
• C)
• D)

____________ nucleotide or nucleoside can be accommodated by group I binding pocket.

• A) Adenine
• B) Thymine
• C) Guanine
• D) Uracil

Due to presence of introns ________ type of RNA is first generated from DNa

• A) Mature mRNA
• B) miRNa
• C) mRNA
• D) Pre mRNa

Pol I is required for the expression of only one gene, that encoding the_____________precursor

• A) rRNA
• B) All given
• C) mRNA
• D) tRNA

TFIIB protein is a __________polypeptide chain, enters the preinitiation complex

• A) double
• B) single
• C)
• D)

The internal guide sequence of group I introns base pairs with ______________.

• A) 3’ splice site sequence
• B) 5’ and 3’ site
• C) 5’ splice site sequence
• D) No specific site

A gene coding sequence is a series of __________ nucleotide codons.

• A) 2
• B) 3
• C) 4
• D) 5

phosphorylation of the CTD leads to an exchange of initiation factors for those factors required for______________

• A) termination
• B) elongation
• C)
• D)

Find the wrong statement in the following:

• A) Primary transcripts of intron-containing genes must have their introns removed before they can be translated into proteins.
• B) Once transcribed into an RNA transcript, the introns must be removed
• C) Introns are very often much longer than the exons they separate
• D) The primary transcript only contains exons

During RNA splicing pre-mRNA is converted into mature mRNA containing __________.

• A) Exons
• B) 3 codons
• C) Introns and Exons
• D) Introns

The coding sequence of a gene is a series of __________ nucleotide codons.

• A) 4
• B) 2
• C) 5
• D) 3

The general transcription factors help polymerase bind to the __________and melt the DNA.

• A) enhancer
• B) promoter
• C)
• D)

Select the incorrect statement regarding spliceosomes:

• A) It is believed that many of the functions of the spliceosome are performed by its RNA components rather than the proteins
• B) Spliceosomes are larger in size compared to a ribosome
• C) In performing even a single splicing reaction, the spliceosome hydrolyzes several molecules of ATP
• D) Spliceosomes complex comprises about 150 proteins and five RNAs

During initial transcription, RNA polymerase produces and releases short RNA transcripts of_____________

• A) <10 nucleotides
• B) <5 nucleotides
• C)
• D)

TFIIE, a general transcription factor consists of_______subunits

• A) 3
• B) 2
• C)
• D)