Under normal conditions, transcription terminates:

• A) At the ends of genes
• B) At the beginning of the gene
• C) In the middle of the gene
• D) Only when DNA is damaged

The spliceosome is composed of approximately

• A) 200 proteins and ten RNAs
• B) 100 proteins and 3 RNAs
• C) 50 proteins and 2 RNAs
• D) 150 proteins and five RNAs

The number of introns within a gene

• A) Varies enormously among different genes
• B) Is always the same in all organisms
• C) Is always low in animal genes
• D) Is always high in yeast genes

The specific nucleotide sequences marking intron–exon borders are found within:

• A) Pre-mRNA
• B) Ribosomal RNA
• C) Mature mRNA
• D) DNA only

U2AF is composed of:

• A) Three subunits
• B) Four subunits
• C) One subunit
• D) Two subunits

The coding sequence in many eukaryotic genes is:

• A) Continuous without breaks
• B) Found only in phage
• C) Interrupted by non-coding stretches
• D) Shorter than bacterial genes

The 3′ splice site is sometimes referred to as the:

• A) Initiator site
• B) Donor site
• C) Enhancer site
• D) Acceptor site

In terms of size, the spliceosome is similar to:

• A) Lysosome
• B) Nucleus
• C) Mitochondrion
• D) Ribosome

Initially, the 5′ splice site is recognized by:

• A) U2AF
• B) U2 snRNP
• C) U1 snRNP
• D) Spliceosome

Which of the following is a class of splicing found in cells?

• A) Nuclear pre-mRNA splicing
• B) Ribosomal RNA splicing
• C) tRNA charging
• D) DNA replication

Unusual termination of transcription may be triggered by:

• A) RNA polymerase activation
• B) Presence of transcription factors
• C) Proper gene regulation
• D) Damaged DNA or unexpected hindrances

The discovery of self-splicing introns demonstrates that:

• A) Proteins alone perform splicing
• B) DNA catalyzes splicing
• C) RNA can catalyze RNA splicing
• D) Ribosomes perform splicing

Unusual termination of transcription may be triggered by:

• A) Damaged DNA or unexpected hindrances
• B) Presence of transcription factors
• C) Proper gene regulation
• D) RNA polymerase activation

The discovery of self-splicing introns demonstrates that:

• A) DNA catalyzes splicing
• B) Proteins alone perform splicing
• C) RNA can catalyze RNA splicing
• D) Ribosomes perform splicing

The specific nucleotide sequences marking intron–exon borders are found within:

• A) DNA only
• B) Pre-mRNA
• C) Mature mRNA
• D) Ribosomal RNA

U2AF is composed of:

• A) Four subunits
• B) Three subunits
• C) Two subunits
• D) One subunit

In terms of size, the spliceosome is similar to:

• A) Ribosome
• B) Mitochondrion
• C) Nucleus
• D) Lysosome

Initially, the 5′ splice site is recognized by:

• A) U2AF
• B) Spliceosome
• C) U1 snRNP
• D) U2 snRNP