The primary input required for homology modeling is

• A) Protein sequence
• B) Protein expression level
• C) Protein function
• D) Protein structure

MEDLINE is the primary resource for biomedical journal articles and millions of citations to articles in biomedical journals can be found here.

• A) True
• B) False
• C)
• D)

Which software tool is commonly used for homology modeling?

• A) SPSS
• B) PyMOL
• C) MODELLER
• D) BLAST

------------is the databases that stores the genome of fruit-fly Drosophila

• A) None of the above
• B) FlyBase
• C) Graphics
• D) Genebank

For simple sequences (not related with down-stream analysis) and annotations and can be submitted through web (if the datasets are small) which does not requires any advanced tools.

• A) NCBI
• B) BANKIt
• C) UniProt
• D) None

------------comprises of more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books.

• A) PUBMED
• B) CINAHL
• C) PsycoINFO
• D) MEDLINE

Sequences are submitted to the databases in order to share them with the scientific community (sometimes they are also required by the Publication and funding agencies to submit them).

• A) False
• B) True
• C)
• D)

Homology modeling is less accurate when:

• A) The target protein has high expression levels
• B) The target and template proteins have low sequence similarity
• C) The target protein has a known structure
• D) The template protein has a different fold than the target protein

The accuracy of homology models depends on

• A) Length of the target protein sequence
• B) Sequence similarity between target and template proteins
• C) Resolution of the template protein structure
• D) Availability of experimental data

PDB is a good resource to get the

• A) Nucleotide structure
• B) RNA structure
• C) Protein structure
• D) DNA structure

PUBMED comprises of more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books.

• A) True
• B) False
• C)
• D)

_____________________is convenient for deposition of gene expression data, as required by funding agencies and journals and it’s also a curated resource for gene expression data where we can do Browsing, querying, analysis and retrieval of the data.

• A) Gene Expression Omnibus
• B) Gene Expression Objectives
• C) None of these
• D) Gene Effective Omnibus

<table align="left" cellpadding="0" cellspacing="0">
<tbody>
<tr>
<td style="vertical-align:top">
<p>----------is a useful sequence converter, basically it recognizes DNA or Protein sequence file and interconvert them between different formats.</p>
</td>
</tr>
</tbody>
</table>

• A) <p>DDBJ</p>
• B) <p>READSEQ</p>
• C) <p>EMBL</p>
• D) <p>NBRF</p>

The process of modeling missing loop regions in homology modeling is called:

• A) Loop modeling
• B) Sequence alignment
• C) Model refinement
• D) Template identification

Salient applications of bioinformatics include ___________.

• A) Genomics, Transcriptomics, Proteomics
• B) System Biology and in personalization of medicines for cure
• C) Metabolomics, Structural Proteomics, Designing Drugs
• D) All

The formation of a specific RNA from a specific DNA

• A) Reproduction
• B) Translation
• C) Transcription
• D) Replication

Adenine and Guanine collectively called Pyrimidine while Cytosine, Uracil, and Thymine are called as Purines.

• A) True
• B) False
• C)
• D)

Start Codon is

• A) UAG
• B) UAA
• C) UGA
• D) AUG

There are mainly four types of ribonucleotides depending upon the types of ______________ present in RNA

• A) Nitrogenous bases
• B) Phosphate
• C) None
• D) Phosphorus

Bioinformatics helps us to understand the systems from small to big like from gene findings to entire system prediction including ____________

• A) Modeling of many biological system
• B) All
• C) Protein structure prediction
• D) None