In PyMOL, the three-dimensional structure of protein is displayed in ................

• A) Selection tool
• B) Object panel
• C) Main viewer window
• D) External GUI

How can data from Prosite help in functional annotation of proteins?

• A) by mapping protein sequence variations in populations
• B) by providing structural information
• C) by identifying conserved domains and motifs associated with functions
• D) by predicting post translational modifications

Which of the following is NOT included among the operations of RCSB PDB?

• A) Visualizing protein structures
• B) Searching for specific protein structures
• C) Analyzing protein sequence alignments
• D) Downloading protein structure files

Prosite uses a specific syntax to represent protein motifs, it’s called

• A) HMM
• B) PSSM
• C) Regular expression
• D) Profile alignment

The purpose of SCAN mode .................

• A) to analyze protein interaction
• B) to retrieve sequences to query sequences
• C) to search for specific patterns
• D) to identify protein domains using sequence profiles

In Phyre2, those sequences have been selected whose identity will be .............. from query sequence. Hint: Protein 3D Structure Prediction

• A) > 20%
• B) > 50%
• C) > 40%
• D) > 30%

What is one of the uses of PyMOL in structural biology?

• A) RNA synthesis
• B) None of these
• C) Protein structure analysis
• D) Genetic engineering

The .................... algorithm is based on information theory combined with Bayesian statistics. Hint: Protein Secondary Structure Prediction

• A) GOR
• B) SPINE-X
• C) PHD
• D) PSIPRED

Fasta format begins with a sign .................

• A) >
• B) #
• C) <
• D) !

Which one of the following programing language does pymol use in the backend?

• A) Ruby
• B) Python
• C) C++
• D) Java

Which type of coding region SNP can potentially alter protein function or structure?

• A) Transition SNPs
• B) Frameshift SNPs
• C) Missense SNPs
• D) Silent SNPs

Which software is commonly used for protein structure visualization and analysis in the Protein Structure?

• A) NMR spectroscopy
• B) RCSB PDB
• C) PyMOL
• D) X-ray crystallography

In the Genbank format, the ‘Locus’ keyword represents ..............

• A) source organism
• B) size of the sequence
• C) genetic position or region being described
• D) name of the sequence file

GeneSeeker is a tool commonly used for predicting _______ in DNA sequences.

• A) Open reading frames (ORFs)
• B) Introns
• C) Promoters
• D) Transcription factors

The transcription starts with the help of …………………………enzyme.

• A) DNA Polymerase
• B) Polymerase
• C) RNA polymerase
• D) DNA polymerase II

AUGUSTUS integrates ab initio gene prediction methods and _______ to improve accuracy.

• A) RNA-seq data
• B) Comparative genomics information
• C) Protein-protein interactions
• D) Phylogenetic analysis

Which computational tool is widely used for predicting ORFs?

• A) PCR
• B) BLAST
• C) Gel-electrophoresis
• D) ORFfinder

____________ is a type of information is typically included in a VCF file?

• A) Phenotypic traits associated with the individuals from which the variants were derived.
• B) Raw sequencing reads for the entire genome.
• C) Protein structure and functional consequences of the genetic variants.
• D) Genotype information, variant calls, and relevant annotations for genetic variants, including SNPs.

The purpose of using oligonucleotide primers in molecular techniques is to

• A) Study gene expression
• B) Amplify DNA sequences through PCR
• C) Perform DNA sequencing
• D) Analyze protein structures

ORFs can represent non-coding regions or .................

• A) Introns
• B) Exons
• C) Pseudogenes
• D) Enhancers