The average number of times any given base in the genome is sequenced is

• A) Coverage
• B) Scaffold
• C) Reads
• D) DNA

If the score if larger than zero, predict it is --------; the higher score, the higher the probability the prediction is true

• A) Receiver/giver
• B) Donor/acceptor
• C)
• D)

The short fragments are compared with each other to discover how they

• A) Read
• B) Form
• C) Overlap
• D) React

ORF Finders tools are

• A) Orf Predictor
• B) NCBI’s ORF Finder
• C) ORF Investigator
• D) All

ALLPATHS-LG can generate high quality genome assemblies using ________by the new generation of sequencers.

• A) Short reads
• B) Long reads
• C) Very Long Reads
• D) Medium size reads

The qualities of genome assemblies are evaluated by ___________.

• A) Presence of expected exons
• B) Poisson distribution
• C) Presence of expected introns
• D) Presence of expected genes

If every nucleotide has ------------ frequency in a position, then the position’s information content is ZERO

• A) 0.25
• B) 1
• C) 100
• D) 0.50

In Lander and Waterman model, if overlap length was larger than a cutoff (T), then the two reads should be merged into a ______.

• A) Contig
• B) Graph
• C) Scaffold
• D) Assembly

A consensus sequence of DNA that has been assembled from overlapping DNA fragments

• A) Scaffold
• B) Primer
• C) Contig
• D) Adapter

-------------------- represent the simplest, most intuitive, solution to the assembly problem.

• A) Agarose gel
• B) FISH
• C) Contigs Overlap
• D) Greedy Graph algorithms

ORF are

• A) Proteins
• B) Open Reading Frame
• C) Online resource formation
• D) Open recording Fragments

------------- are the most common source of Mis-assemblies

• A) Repeats
• B) DNA Sequence
• C)
• D)

In Assembly Pipeline Quality Screening is done while satisfying the following matrices, except _______.

• A) Library quality
• B) Sequencing Run Quality
• C) Poisson distribution
• D) Read Quality

_______can be defined as the average number of times any given base in the genome is sequenced.

• A) Contig
• B) Scaffold
• C) Calculations Coverage
• D) Assembly

Greedy assemblers can detect ------------- and high-scoring ones that are resulted from repetitive sequences

• A) True sequence
• B) False overlaps
• C)
• D)

Coverage can be derived by dividing the total length of acquired sequences by the -----------------

• A) genome Base
• B) RNA Length
• C) DNA Sequence
• D) Genome length

ALLPATHS-LG requires _________ computer operating system.

• A) 32 bit Linux
• B) 32 bit Windows
• C) 64 bit Linux
• D) 64 bit Windows

Gene finding, especially in ------------------ starts form searching for an open reading frames

• A) Human
• B) Prokaryotes
• C) Chimpanzee
• D) Eukaryotes

Related species genomes helps in

• A) Guiding the assembly of the target species
• B) All
• C) Verifying the completeness of the assembly
• D) The sequencing approaches and assembly strategies are interdependent

Assembly Pipeline process can be divided into following major phases, except ______.

• A) Unitiging
• B) Repeat resolution
• C) Assembling
• D) Scaffolding