The study of characteristics and regulation of the functional RNA transcript population of a cell/s or organism at a specific time is:

• A) Genomics
• B) Proteomics
• C) Lipidomics
• D) Transcriptomics

The population of _______ expressed by a genome at any given time is transcriptomics

• A) tRNA
• B) mRNA
• C) all of these
• D) rRNA

Dicer cleaves double-stranded RNA (dsRNA) and pre-microRNA into short double-stranded RNA fragments called

• A) • siRNA
• B) • dsRNA
• C) • snRNA
• D) • ssRNA

siRNA’s better target for efficient work is

• A) 3’ UTR
• B) 3’ AGT
• C) 5’ AGT
• D) 5’ UTR

Unwinding of double-stranded siRNA occurs by

• A) ATP dependent polymerase
• B) ATP dependent helicase
• C) ATP independent polymerase
• D) ATP independent helicase

30% of mammalian mRNAs are regulated by ______.

• A) Ribosomal RNA
• B) Nuclear RNA
• C) miRNAs
• D) Transfer RNA

RISC is a _______ kDa, RNA-multiprotein complex

• A) 500
• B) 50
• C) 5 x 10
• D) 5

Helicos
Pacific Biosciences
Oxford nanopore
The are related with what?

• A) 3GS
• B) PCR
• C) Gene cloning
• D) 2d PAGE

Virtual Terminator in Helicos prevents incorporation of multiple __________ per cycle

• A) histone
• B) nucleic acid
• C) peptides
• D) nucleotides

How many types of semi conductor chips:

• A) 7
• B) 5
• C) 3
• D) 10

Drosha and Dicer are ____ enzymes.

• A) RNase II
• B) DNase III
• C) DNase II
• D) RNase III

RISC mediates which cellular function:

• A) • Degrades mRNA
• B) • Starts Transcription
• C) • Degrades tRNA
• D) • Helps translation

Assigning identities and functions to sequences within the genome is called ________.

• A) Genome Sequencing
• B) Genomic evaluation
• C) cDNA formation
• D) Genome annotation

Transcription factors bind to specific __________.

• A) cDNA sequences
• B) RNA sequences
• C) Protein sequences
• D) DNA sequences

Mouse and human genomes each contains approximately ______ protein coding genes.

• A) 23000
• B) 10000
• C) 25000
• D) 5000

DNA Microarray technology is widely used for genetic analysis. The technique is basically an evolution of another process known as:

• A) Western blotting
• B) Southern hybridization
• C) Sanger sequencing
• D) Northern hybridization

Microarray technology evolved from ______, where fragmented DNA is attached to a substrate and then probed with a known DNA sequence.

• A) Southern blotting
• B) Northern blotting
• C) Western blotting
• D) Gel electrophoresis

Ensembl core databases store genome _________ information.

• A) Sequence
• B) RFLP
• C) Sequence and annotation
• D) SNPs

Ensembl is a joint project between these 3 organizations.

• A) EMBL, EBI, NCBI
• B) EMBL, EBI, FBI
• C) EMBL, EBI, WTSI
• D) EMBL, EBI, CIA

Mouse genome contains ___ CpG islands than human.

• A) equal
• B) permanent
• C) more
• D) fewer