MCQ Bank
Which is basic strategy for producing transgenic animals?
- A) Loss and gain of function
- B) Gain of function
- C) Loss of function
- D) Complex function
Which method does not require live transgenic offspring to test for the presence of the desired transgene?
- A) None of the given
- B) Pronuclear Microinjection
- C) Embryonic stem cell mediated transgenesis
- D) Retrovirus mediated transgenesis
Earlier pituitary-derived hGH was used but later on it was prohibited when found associated with ___________________
- A) Tay Sachs Disease
- B) Down syndrome
- C) Huntington disease
- D) Creutzfeldt Jakob disease
Which of one is found in the MMR vaccine?
- A) Rubella vaccine
- B) Mumps vaccine
- C) All of the given
- D) Measles vaccine
It has been shown that erythropoietin (EPO) can upsurge ____________absorption by quashing the hormone hepcidin.
- A) Chloride
- B) Iodine
- C) Magnesium
- D) Iron
Insulin is a peptide hormone consisting of 51 amino acids. Insulin is stored in the form of proinsulin which contains two polypeptide chains, A and B, and is connected with a third peptide C chain. How are many amino acid in A and B CHAIN?
- A) A=30, B=21
- B) A=21, B=30
- C) A=31, B=20
- D) A=20, B=31
Of the various forms, the predominant form of hGH is 22 kDa protein of ___________ amino acids with ___________disulfide bonds.
- A) 190, two
- B) 191, two
- C) 193, three
- D) 192, three
Who is the manufacturer of “Espogen” that is trade name of recombinant erythropoietin (EPO)?
- A) Cadila Healthcare Ltd.
- B) Shantha Biotechnics Ltd.
- C) Amgen
- D) LG Life Sciences
Which one is a cheaper alternative of tissue plasminogen activator that can be used as a thrombolytic in acute treatment?
- A) Streptokinase
- B) Reteplase
- C) Alteplase
- D) Tenecteplase
Which is used in various diseases such as pulmonary embolism, myocardial infarction, stroke, and thrombolysis?
- A) Blood clotting factor VIII
- B) Human growth hormone
- C) Tissue plasminogen activator
- D) Erythropoietin
The Varicella vaccine is administered to prevent
- A) Mumps
- B) Influenza
- C) Rubella
- D) Chicken pox
____________is also an FDA-approved drug for the treatment of acute myocardial infarction and it has more convenient administration and faster thrombolysis than Alteplase.
- A) Streptokinase
- B) Tenecteplase
- C) None of the given
- D) Reteplase
Tissue plasminogen activator (tPA) is another kind of serine protease protein that is involved in __________________
- A) The breakdown of insulin in humans
- B) The breakdown of blood clots in humans
- C) The breakdown of glycogen in humans
- D) The breakdown of RBCs in humans
It has been reported that ___________ has its primary effect on red blood cells by protecting the blood cells from going to the apoptosis pathway.
- A) Human growth hormone
- B) Blood clotting factor VIII
- C) Erythropoietin
- D) Tissue plasminogen activator
Louis Pasteur generalized Edward Jenner’s idea by developing what he called a__________________, now termed an antitoxin.
- A) Herpes simplex vaccine
- B) Polio vaccine
- C) Sabin and Salk vaccine
- D) None of the given
Live Attenuated vaccine are used to confer
- A) Passively immunity
- B) Adaptive immunity
- C) Memory induced immunity
- D) Innate immunity
Which of following statement is correct about erythropoietin (EPO)?
- A) EPO can upsurge iron absorption by quashing the hormone hepcidin
- B) EPO plays an important role in the wound healing process
- C) All of the given
- D) EPO plays an important role in neuronal injury
The most stable of all vaccine types are
- A) Attenuated vaccines
- B) Inactivated vaccines
- C) Subunit vaccines
- D) DNA vaccines
In the beginning, efforts were made to isolate mRNA for pre and proinsulin from rat islets of Langerhans of pancreas and to synthesize ____________
- A) RNA
- B) cDNA
- C) DNA
- D) Protein
Which is used for the treatment of hypopituitary dwarfism and Turner Syndrome?
- A) Recombinant tissue plasminogen activator
- B) Recombinant erythropoietin
- C) Recombinant human growth hormone
- D) Recombinant blood clotting factor VIII