There are ___________ repeats of CTD are present in the yeast Pol II

• A) 12
• B) 27
• C)
• D)

Pol I is required for the expression of only one gene, that encoding the_____________precursor

• A) tRNA
• B) All given
• C) mRNA
• D) rRNA

TFIIE, a general transcription factor consists of_______subunits

• A) 3
• B) 2
• C)
• D)

During initial transcription, RNA polymerase produces and releases short RNA transcripts of_____________

• A) <10 nucleotides
• B) <5 nucleotides
• C)
• D)

____________polymerase can initiate a new RNA chain on a DNA template

• A) RNA
• B) DNA
• C)
• D)

A gene coding sequence is a series of __________ nucleotide codons.

• A) 5
• B) 2
• C) 4
• D) 3

The branchpoint site in RNA editing, is present on ___________.

• A) DNA ligase
• B) Exons
• C) Introns
• D) Both introns and Exons

TFIIB protein is a __________polypeptide chain, enters the preinitiation complex

• A) single
• B) double
• C)
• D)

TAF42 and TAF62 from Drosophila have been shown to form a structure similar to that of the ___________tetramer of histones

• A) H3.H2
• B) H1.H3
• C) H1.H4
• D) H3.H4

____________ nucleotide or nucleoside can be accommodated by group I binding pocket.

• A) Adenine
• B) Thymine
• C) Guanine
• D) Uracil

TFIIH controls the ____________transition of the preinitiation complex to the open complex

• A) ATP-dependent
• B) AMP-dependent
• C)
• D)

large subunit of ___________has a carboxy-terminal domain (CTD), which is referred to as the “tail”

• A) Pol I
• B) Pol II
• C)
• D)

All eukaryotes have __________ types of RNA polymerases

• A) 5
• B) 7
• C) 2
• D) 3

Select the incorrect statement regarding spliceosomes:

• A) In performing even a single splicing reaction, the spliceosome hydrolyzes several molecules of ATP
• B) It is believed that many of the functions of the spliceosome are performed by its RNA components rather than the proteins
• C) Spliceosomes complex comprises about 150 proteins and five RNAs
• D) Spliceosomes are larger in size compared to a ribosome

transition from initiation to elonagation phase involves the ___________enzyme shedding most of its initiation factors

• A) Pol II
• B) Pol I
• C)
• D)

The general transcription factors help polymerase bind to the __________and melt the DNA.

• A) promoter
• B) enhancer
• C)
• D)

RNA polymerase starts most transcripts with _____________ ribonucleotide

• A) thymine
• B) adenine
• C)
• D)

Spliceosomes are huge molecular machine that mediate _______________ reactions

• A) High energy
• B) Neutralization
• C) Transesterification
• D) Hydrolysis

During elongation, the enzyme adds ______________nucleotide at a time to the growing RNA transcript

• A) 1
• B) 2
• C) 5
• D) 3

phosphorylation of the CTD leads to an exchange of initiation factors for those factors required for______________

• A) termination
• B) elongation
• C)
• D)