The introns and exons are distinguished through ______________.

• A) Only 3’ splice site
• B) Only 5’ splice site
• C) 5’ and 3’ splice site
• D) 5’ and 3’ side

During the removal of intron, the first reaction is triggered by:

• A) 2’-OH of the conserved A at the branch site
• B) 5’ phosphoryl group of conserved G at the splice site
• C) 2’-OH of the conserved G at the branch site
• D) 3’ phosphoryl group of conserved G at the splice site

transition from initiation to elonagation phase involves the ___________enzyme shedding most of its initiation factors

• A) Pol II
• B) Pol I
• C)
• D)

large subunit of ___________has a carboxy-terminal domain (CTD), which is referred to as the “tail”

• A) Pol II
• B) Pol I
• C)
• D)

The branchpoint site in RNA editing, is present on ___________.

• A) Introns
• B) Exons
• C) DNA ligase
• D) Both introns and Exons

The coding sequence of a gene is a series of codons that specifies the ____________ of amino acids in the polypeptide product.

• A) Linear sequence
• B) RNA sequence
• C) Structure
• D) DNA

The “transient excursion” model proposes transient cycles of forward and reverse translocation of__________________

• A) DNA polymerase
• B) RNA polymerase
• C)
• D)

There are ___________ repeats of CTD are present in the yeast Pol II

• A) 27
• B) 12
• C)
• D)

Spliceosomes are huge molecular machine that mediate _______________ reactions

• A) Transesterification
• B) Neutralization
• C) Hydrolysis
• D) High energy

During elongation, the enzyme adds ______________nucleotide at a time to the growing RNA transcript

• A) 5
• B) 3
• C) 2
• D) 1

RNA polymerase starts most transcripts with _____________ ribonucleotide

• A) thymine
• B) adenine
• C)
• D)

TFIIH controls the ____________transition of the preinitiation complex to the open complex

• A) AMP-dependent
• B) ATP-dependent
• C)
• D)

__________ classes of splicing found in the cell

• A) 3
• B) 5
• C) 2
• D) 4

The 5’ splice site is recognized by:

• A) U5 SnRNP
• B) U2AF
• C) U1 SnRNP
• D) U4 SnRNP

All eukaryotes have __________ types of RNA polymerases

• A) 2
• B) 5
• C) 7
• D) 3

TAF42 and TAF62 from Drosophila have been shown to form a structure similar to that of the ___________tetramer of histones

• A) H1.H3
• B) H3.H2
• C) H1.H4
• D) H3.H4

.......invokes a flexible element within the polymerase that allows a module at the front of the enzyme, containing the active site.

• A) Inchworming
• B) Scrunching
• C) transient excursion
• D) Scrunching and Inchworming

Bacteria have _________ types of RNA polymerase

• A) 5
• B) 3
• C) 2
• D) 1

____________ is known as the minor form of the spliceosome.

• A) Special spliceosome
• B) GC-AT spliceosome
• C) AT-AC spliceosome
• D) AC-TG spliceosome

The 5’ splice site is recognized by:

• A) U2AF
• B) U4 SnRNP
• C) U5 SnRNP
• D) U1 SnRNP