BamHI is an enzymes used in the creation of ____ by using the phage-ʎ vector EMBL3A

• A) Mutated DNA
• B) genomic DNA library
• C) Protein molecules
• D) rRNA molecules

Immunochemical screening involves the use of

• A) PCR
• B) Antigens
• C) DNA
• D) Antibodies

Functional complementation is also possible in

• A) Transgenic mitochondria
• B) Transgenic animals and plants
• C) Artificial animals and plants
• D) Non-Transgenic animals and plants

Which statement is correct for bacterial artificial chromosomes

• A) They are simply plasmids designed for the cloning of very long segments of DNA
• B) They are simply DNA molecules designed for the cloning of proteins
• C) They are protein molecules designed for the recombination of RNA
• D) They are simply plasmids designed for the cloning of very short segments of DNA

Major screening strategies involve _____

• A) Genetic methods
• B) Screening expression libraries
• C) All of these
• D) Sequence-dependent screenings

Genomic DNA library is constructed using _______ cloning vectors

• A) low copy and capacity
• B) low capacity
• C) low copy number
• D) high capacity

Cytokines, Interferon gamma & Interleukin (IL-1), are produced by …………………………

• A) neutrophils
• B) T helper cells
• C) basophils
• D) macrophages & monocytes

Hemolytic disease of newborn of is caused by ……………………

• A) cytotoxic hypersensitivity
• B) cell mediated hypersensitivity
• C) immune complex hypersensitivity
• D) immediate hypersensitivity

Type II hypersensitivity is also known as----------

• A) cell mediated hypersensitivity
• B) Cytotoxic hypersensitivity
• C) Anaphylactic reactions
• D) Immune complex hypersensitivity

Cytokines are -------

• A) Diverse group of antibody proteins
• B) Diverse group of non-antibody cells
• C) Diverse group of non-antibody lipids
• D) Diverse group of non-antibody proteins

Allergic asthma and hay fever are examples of -------

• A) Type I Hypersensitivity
• B) Type II Hypersensitivity
• C) Type III Hypersensitivity
• D) Type IV Hypersensitivity

Chemokines are cytokines that are responsible for …………………….

• A) leucocytes killing
• B) leucocytes proliferation
• C) leucocytes migration
• D) leucocytes inhibition

Hypersensitivity I is mediated by ------

• A) IgG
• B) IgM
• C) IgE
• D) IgA

In type III hypersensitivity, aggregated …………….. form micro thrombus.

• A) macrophages
• B) complement proteins
• C) platelets
• D) neutrophils

Tumor Necrosis Factor-Alpha is produced by activated ………………… in response to microbes or their products.

• A) monoctyes
• B) macrophages
• C) lymphocytes
• D) T-cells

Tuberculin test is used to diagnose ……………………….. reaction

• A) Hypersensitivity type III
• B) Hypersensitivity type II
• C) Hypersensitivity type I
• D) Hypersensitivity type IV

These all cells are involved in delayed type hypersensitivity EXCEPT …………………

• A) Monocytes
• B) Macrophages
• C) T-cells
• D) B-cells

Delayed type hypersensitivity is -------

• A) Type III
• B) Type I
• C) Type II
• D) Type IV

Antibody dependent Cellular Cytotoxicity is another form of Type II hypersensitivity causes the lysis target cells primarily by ………………

• A) neutrophils
• B) NK cells
• C) macrophages
• D) eosinophils

Anaphylactic reactions usually take ………………… to occur.

• A) 1-2 days
• B) 1-2 minutes
• C) 10-12 hrs
• D) 15-30 minutes