Kappa and lambdaarethe types of.......... of antibodies.

• A) Heavy chain
• B) Variable region
• C) Light chains
• D) Constant region

PRRs recognize various molecular patterns on the surface of pathogens which are called as pattern associated molecular patterns (PAMPs). Which of the following is not a PAMP molecule?

• A) Antibodies
• B) Lipopolysacchrides
• C) Cell wall component
• D) Flagellins

neare the proteinsthat bind with iron and deprive bacteria from iron.

• A) Lactoferrin and interferon
• B) Transferrin and interferon
• C) Interleukin and lactoferrin
• D) Lactoferrin and transferrin

These all are example of live attenuated vaccine EXCEPT …………………

• A) Smallpox
• B) Hepatitis A Virus
• C) Rabies
• D) Measles

The substrate of horseradish peroxidase is..............

• A) O-
• B) O2
• C) H2O
• D) H2O2

Th1 cells release cytokine like IFNγ upon activation which is inhibitory for ……………

• A) Th2 cells
• B) macrophages
• C) CTL
• D) mast cells

Following route of administration of vaccine is considered as appropriate in term of optimum immune response

• A) sub-cutaneous
• B) Intravenous
• C) Gastric
• D) Intramuscular

The adverse effect of Rubella vaccination could be ………………….

• A) Malaise
• B) Neurological disorder
• C) Fever
• D) Joint pain

The principles of hybridoma formation include all of the following EXCEPT...................

• A) Injection of mice with an antigen
• B) Fusion of lymphocyte with Myeloma cell
• C) Isolation of T-lymphocyte from spleen of mice
• D) Selection hybridoma cell

Th2 cells upon activation secrete cytokines like IL-4 and IL-5 which activate …………………

• A) CTL
• B) B-cells
• C) APC
• D) Macrophages

The process of engulfing the invading orinfectious agent by phagocytes is known as......

• A) Lysosomal Lysis
• B) Engulfolysis
• C) Phagocytosis
• D) Parthenogenesis

These all statements are true for tolerance EXCEPT ………….

• A) Can be against non-self antigens
• B) Tolerance to tissue and cell antigens can not be induced artificially
• C) Modification of antigens lead towards tolerance
• D) Specific Immunological unresponsiveness

The region on antibody which interact with the antigenic determinant of an antigen is known as...........

• A) Determinant
• B) Paratope
• C) Native determinant
• D) Epitope

Immunodominant Peptides are simple and easy to prepare and they are incorporated with …………… to induce humoral & cell-mediated response.

• A) anti-idiotype antibodies
• B) cloned viral peptides
• C) MHC
• D) polysaccharide antibodies

The kinetics of primary antibody response against T-dependent antigens consist of ............ phases.

• A) 3
• B) 2
• C) 4
• D) 6

Passive transfer of cell mediated immunity is carried out for the treatment of …………………………

• A) influenza
• B) diphtheria
• C) cancer & immunodeficiency
• D) botulism

MHCII molecules contain highly conserved regions for binding to CD4 receptors.

• A) α 1 & β 2
• B) α2 & β 2
• C) α 2 & β 1
• D) α3 & β2

Edema is the ……………………… of effected area due to additional accumulation of fluid into interstitial space of the region.

• A) redness
• B) swelling
• C) damage
• D) warming

Antibodies fragments are generally produced by the action of..... Enzyme.

• A) Pepsin
• B) Papain
• C) Pectinase
• D) cellulase

Lymphokine activated cells are specific for the killing of ………………… cells.

• A) parasitic
• B) bacterial
• C) tumor
• D) viral