The mass of water H2O is ________.

• A) 16 Daltons
• B) 18 Daltons
• C) 10 Daltons
• D) 17 Daltons

In shortgun sequencing technique the genome fragment length is ____.

• A) 500 - 700
• B) 1000 or above
• C) 800 - 1000
• D) 200 - 400

Mass spectrophotometer is used for the removal of …………………

• A) Protein
• B) Ions
• C) Fragments
• D) None of the above

Sanger used _____ to digest insulin protein.

• A) Protease enzyme
• B) Restriction enzyme
• C) Sonication
• D) Nuclease enzyme

Which of the following is incorrect regarding Ab Initio–Based Methods?

• A) This type of method predicts the secondary structure based on a single query sequence
• B) It measures the relative propensity of each amino acid belonging to a certain secondary structure element
• C) The propensity scores are derived from known crystal structures
• D) This type of method predicts the secondary structure based on a multiple query sequence

Most fragment assembly algorithm consists of the ______ steps.

• A) Overlap and Layout
• B) Overlap, Layout and Consensus
• C) Layout and Consensus
• D) Overlap and Consensus

If several alanine’s found in the sequence, then it anticipates that a ______ secondary structure may be formed by them.

• A) Loops
• B) Coils
• C) Alpha Helices
• D) Beta Sheets

Which amino acid form disulphide bridge

• A) Glutamine
• B) Proline
• C) Alanine
• D) Cysteine

Tyrosine (Tyr) is most likely to found in ______.

• A) Turns
• B) Helices
• C) Coils
• D) Beta Sheets

The mass of ammonia is NH3 _______.

• A) 18 Daltons
• B) 16 Daltons
• C) 19 Daltons
• D) 17 Daltons

The first step is to predict secondary structure from …………..

• A) RNA
• B) Primary
• C) DNA
• D) None of the above

Alu fragment is ……………… bp long repeated fragment

• A) 800
• B) 300
• C) 500
• D) 400

which algorithm is used for finding the shortest superstring of a substring/read of genome?

• A) Superstring Problem Algorithm
• B) Shortest Superstring Problem Algorithm
• C) String finding Algorithm
• D) Shortest read Algorithm

In smith and waterman algorithm the initial matrix is created with _____ columns and _____ rows.

• A) M+1 and N+1
• B) M+1 and N
• C) M and N+1
• D) M and N

Which of the following is un true regarding Chou–Fasman methods?

• A) First-generation method
• B) Developed in the 1970s,
• C) Suffer from the fact that the prediction rules are somewhat arbitrary
• D) Based on single sequence statistics with clear relation to known protein-folding theories

The most frequent N-terminal ions of peptide are called _____.

• A) b-ions
• B) y-ions
• C) a-ions
• D) z-ions

Find the lexicographic order of {TAT, ATG, TGG, GGT, GTG, TGC}.

• A) TAT, TGC, TGG, GTG, GGT, ATG
• B) ATG, GTG, TAT, GGT, TGC, TGG
• C) ATG, GGT, GTG, TAT, TGC, TGG
• D) TGG, TGC, TAT, GTG, GGT, ATG

The first step of Needleman-wunsch algorithm is to ______.

• A) Matrix filling with the appropriate scores
• B) Traceback the sequences for a suitable alignment
• C) Initialization of matrix with gap penalty
• D) Initialization of a matrix with zero’s

Steps of mass spectrometry involves ______.

• A) Protein --> Peptide --> small fragmentation --> measure mass
• B) Peptide --> small fragmentation --> measure mass
• C) Protein --> small fragmentation --> measure mass
• D) Small fragmentation --> Peptide --> Proteins --> measure mass

BAC stands for …………………..

• A) None of the above
• B) Bacterial artifact chromosome
• C) Blood alcohol concentration
• D) Bacterial artificial chromosome