The mouse genome is about ____ smaller than the human genome.

• A) 50%
• B) 33%
• C) 14%
• D) 99%

Approximately ____ of mouse genes have a homologue in the human genome.

• A) 99%
• B) 10%
• C) 33%
• D) 50%

Genes can be identified in vitro using ______.

• A) Genomic methods
• B) Genomic selection
• C) Computational methods
• D) Genome sequencing

_____ is a model organism in Animal Biology and Genetics.

• A) Cow
• B) Drosophila
• C) Rat
• D) Mouse

Transcription factors are ________ that bind to the DNA and help to control gene expression.

• A) Proteins
• B) Amino acid
• C) cDNA
• D) RNA

DNA microarray has many applications. All of the following are applications of the technique EXCEPT:

• A) Assessment of gene expression levels
• B) Analysis of protein function
• C) Discovery of new genes
• D) Evaluation of micro RNA levels

In human genome, males mutation rate is _______ as in the female

• A) Four times
• B) Equal
• C) Twice
• D) Three times

Researchers can use the UCSC Genome Browser to find information in the genomes that have been ________.

• A) Deleted
• B) Sequenced
• C) Generated
• D) Removed

The --------------- nucleotide distribution is information is a basis for translation start prediction

• A) Unbiased
• B) Biased
• C) RNA
• D) DNA

For genome assembly try different assemblers as there is no _________.

• A) Libraries
• B) Duplicates
• C) Best assembler
• D) Parameter

ALLPATHS-LG assemblies are not necessarily__________, but instead are presented in the form of a ______.

• A) Linear, graph
• B) Linear, Circle
• C) Graph, Line
• D) Circular, graph

The average number of times any given base in the genome is sequenced is

• A) Coverage
• B) Scaffold
• C) Reads
• D) DNA

If the score if larger than zero, predict it is --------; the higher score, the higher the probability the prediction is true

• A) Receiver/giver
• B) Donor/acceptor
• C)
• D)

The short fragments are compared with each other to discover how they

• A) Read
• B) Form
• C) Overlap
• D) React

ORF Finders tools are

• A) Orf Predictor
• B) NCBI’s ORF Finder
• C) ORF Investigator
• D) All

ALLPATHS-LG can generate high quality genome assemblies using ________by the new generation of sequencers.

• A) Short reads
• B) Long reads
• C) Very Long Reads
• D) Medium size reads

The qualities of genome assemblies are evaluated by ___________.

• A) Presence of expected exons
• B) Poisson distribution
• C) Presence of expected introns
• D) Presence of expected genes

If every nucleotide has ------------ frequency in a position, then the position’s information content is ZERO

• A) 0.25
• B) 1
• C) 100
• D) 0.50

In Lander and Waterman model, if overlap length was larger than a cutoff (T), then the two reads should be merged into a ______.

• A) Contig
• B) Graph
• C) Scaffold
• D) Assembly

A consensus sequence of DNA that has been assembled from overlapping DNA fragments

• A) Scaffold
• B) Primer
• C) Contig
• D) Adapter