MCQ Bank
_____________ is described as the most redox-active nitrogeneous base in DNA.
- A) Adenine
- B) Guanine
- C) Thymine
- D) Cytosine
__________ are short DNA oligonucleotides (12-40-mer) able to hybridize with specific target sequences.
- A) DNA Probes
- B) Antibody
- C) DNA Dendrimers
- D) Aptamers
The convenient oxidation of ______________ base is helpful in the detection of target molecule under ambient conditions.
- A) Thymine
- B) Adenine
- C) Guanine
- D) Cytosine
__________ interaction between ribose sugar and histones happen during binding of DNA with Histones.
- A) Hydrogen Bonding
- B) Polar Interaction
- C) Salt Bridge
- D) Non-Polar Interaction
Nucleosomes fold up to form a 30- nanometer chromatin fiber, which forms loops averaging______ nanometers in length.
- A) 200
- B) 300
- C) 400
- D) 450
__________ is a process which decreases the fluorescence intensity of a substance.
- A) Impedance
- B) Fluorescence
- C) Dissipation
- D) Quenching
____________ interactions between the N-terminal tail of Histone minor groove of DNA occur during binding of DNA with histones.
- A) Non-Polar interaction
- B) Hydrogen Bonding
- C) Non-Specific
- D) Polar interaction
When human DNA is exposed to γ rays and heavy particles, there is an increase in the _______ main degraded products of guanine.
- A) 3
- B) 4
- C) 1
- D) 2
A typical molecular beacon probe is ________ nucleotides long.
- A) 10
- B) 15
- C) 35
- D) 25
Atomic number of Cesium is ___________.
- A) 70
- B) 90
- C) 55
- D) 85
_____________ are single stranded DNA or RNA molecules that fold into defined secondary structures and bind to targets with high affinity and specificity.
- A) Antigen
- B) Antibody
- C) Probe
- D) Aptamers
______________ is a combination of two non-covalent interactions such as hydrogen bonding and electrostatic interaction within the two biological molecules.
- A) Hybridization
- B) Salt Bridge
- C) Ionic interactions
- D) Chemotaxis
__________ is oxidizes more easily as compared to the other bases of DNA.
- A) Adenine
- B) Cytosine
- C) Guanine
- D) Thymine
In Genomic DNA libraries, the appropriately sized random fragments can be produced by _________
- A) Lysozymes
- B) Polymerases
- C) Ligases
- D) Restriction endonucleases
Major screening strategies involve _______
- A) All of these
- B) Genetic methods
- C) Sequence-dependent screenings
- D) Screening expression libraries
cDNA is sequence which lacks ________ sequences.
- A) introns
- B) untraslated exons
- C) none of these
- D) exons
Genomic DNA library is constructed using _______ cloning vectors.
- A) low capacity
- B) high capacity
- C) low copy number
- D) low copy and capacity
BamHI is an enzymes used in the creation of ______ by using the phage-ʎ vector EMBL3A.
- A) rRNA molecules
- B) Mutated DNA
- C) Protein molecules
- D) Genomic DNA library
The ________ with specific primers could be used to isolate genes directly from genomic DNA
- A) PCR
- B) SNPs
- C) AFLP
- D) RFLP
Synthesis of cDNA from RNA is done using _____
- A) inverse-PCR
- B) reverse-PCR
- C) qPCR
- D) RT-PCR